STIs and Sex Toys: Part 2 HPV is particularly difficult to clean off of sex toys. In our last carousel we learned that HPV can survive on sex toys for up to Using sex toys can enhance your sexual experiences, but it's important to use them safely to prevent STIs. Here are some essential tips:, Never share a sex toy., Use plenty of lube and a condom., Sex toys come into direct contact with rectal and vaginal fluids, and mucous membranes. This means that HIV could be passed on from sharing an uncleaned sex toy. Although using sex toys List of sexual practices and risk of HIV infection; ninth of sixteen advertisement posters by the American Red Cross promoting education about AIDS. Colour lithograph, 1990. Wellcome Collection